Soft-Template Construction of 3D Macroporous Polypyrrole Scaffolds

Polypyrrole Soft Actuators

Macroporous nanowire nanoelectronic scaffolds for synthetic tissues.

The development of three-dimensional (3D) synthetic biomaterials as structural and bioactive scaffolds is central to fields ranging from cellular biophysics to regenerative medicine. As of yet, these scaffolds cannot electrically probe the physicochemical and biological microenvironments throughout their 3D and macroporous interior, although this capability could have a marked impact in both el...

Macroporous polypyrrole-TiO2 composites with improved photoactivity and electrochemical sensitivity.

Macroporous polypyrrole (PPy)-TiO2 composites were prepared by in situ oxidative polymerization of pyrrole in the macropores of TiO2. The formation mechanism of the PPy nanoparticles, including nucleation and further growth, was proposed by studying the particle growth process with increasing reaction time. The special growth process favors the formation of good cohesion and stabilized interfac...

Multi-nozzle deposition for construction of 3D biopolymer tissue scaffolds

Purpose – To introduce recent research and development of biopolymer deposition for freeform fabrication of three-dimensional tissue scaffolds that is capable of depositing bioactive ingredients. Design/methodology/approach – A multi-nozzle biopolymer deposition system is developed, which is capable of extruding biopolymer solutions and living cells for freeform construction of 3D tissue scaffo...

3D Differentiation of Neural Stem Cells in Macroporous Photopolymerizable Hydrogel Scaffolds

Neural stem/progenitor cells (NSPCs) are the stem cell of the adult central nervous system (CNS). These cells are able to differentiate into the major cell types found in the CNS (neurons, oligodendrocytes, astrocytes), thus NSPCs are the mechanism by which the adult CNS could potentially regenerate after injury or disorder. Microenviromental factors are critical for guiding NSPC differentiatio...